Formation and function of GnRH-induced subnormal corpora lutea in cyclic ewes

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Formation and function of GnRH-induced subnormal corpora lutea in cyclic ewes.

Of 19 dioestrous ewes given 50 micrograms GnRH on Day 10 of the oestrous cycle, 15 (79%) formed corpora haemorrhagica within 2 days after injection of GnRH. After excision of the Day 10 spontaneous CL, the GnRH-induced CL were short lived when compared to spontaneous CL in saline-treated ewes (3.1 +/- 0.4 vs 17.3 +/- 0.3 days, respectively). Hysterectomy of ewes bearing the GnRH-induced CL prev...

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The production of luteal oxytocin in ewes, resulting from the intrajugular injection of 200 micrograms of PGF2 alpha, could be determined by the increase in intramammary pressure. This simple indirect method of measuring the activity of the corpus luteum enabled easy detection of renewed post-partum ovulation or the onset of pregnancy. The response was monitored every two days between Days 0 an...

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Formation and maintenance of corpora lutea in laboratory animals.

T HE past decade has witnessed a revival of interest in the mammalian corpus luteum. The availability of new techniques is in part responsible but a more important factor has been the increasing use of cows, sheep, pigs and even women as experimental species. The use of these mammals has uncovered, to a much greater degree than was expected, a diversity in the physiology of the corpus luteum, a...

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Effect of successive enucleations of bovine corpora lutea on formation and function of subsequent luteal tissue.

I T has been demonstrated that exogenous progesterone exerts a stimulatory effect on ovulation in cattle (Hansel and Trimberger, 1952) as well as an inhibitory effect (Ulberg, Christian and Casida, 1951; Trimberger and Hansel, 1955; Nellor and Cole, 1957; Labhsetwar et al., 1964). However, the role of endogenous luteal progesterone in the regulation of bovine corpus luteum formation and functio...

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Role of the uterus in early regression of corpora lutea induced by the ram effect in seasonally anoestrous Barbarine ewes.

The involvement of the uterus in early regression of corpora lutea induced by the ram effect was studied in seasonally anoestrous Barbarine ewes. In experiment 1, group I was only submitted to the male effect (control, n = 15) while group II (n = 14) was injected every 12 h with flunixin meglumine, a PGF2 alpha synthetase inhibitor (finadyne), from day 3 to day 6 (day 0: day of ram introduction...

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ژورنال

عنوان ژورنال: Reproduction

سال: 1989

ISSN: 1470-1626,1741-7899

DOI: 10.1530/jrf.0.0870265